
Company Introduction
Belief BioMed Inc. (BBM) is a high-tech company that integrates the development, manufacturing and clinical application of gene therapy products. The company is committed to providing innovative and more effective gene therapies for monogenic diseases, neurodegenerative diseases, age-related degenerative diseases and some other major malignant diseases through safe and efficient virus vector technology.
BBM has developed hundreds of key vector technologies, including HEK293 cell suspension serum-free culture process and full-scale chromatography purification process, and has established the commercial production platform for gene therapy drugs in China. The company has been building up its capabilities in a variety of fields including novel AAV capsids targeting different tissues, efficient transgene expression cassette design, and advanced clinically applicable vector manufacturing process. It has also established an extensive R&D pipeline covering a wide range of major, unmet clinical needs in therapeutic areas such as hemophilia, Parkinson's disease, arthritis, neuromuscular disease, etc. Several product pipelines have entered clinical studies or IND filings.
The CTA for BBM-H901, an AAV gene therapy drug for prevention of bleeding in adult male patients with hemophilia B, which was independently developed and manufactured by Belief BioMed, was officially approved by China National Medical Products Administration (NMPA). It is the first gene therapy under development for treatment of hemophilia in China. In 2022, the results of clinical studies related to BBM-H901 were successively published in two prestigious international journals, i.e. The Lancet Haematology and New England Journal of Medicine. In the same year, BBM-H901 was granted Orphan Drug Designation (ODD) by U.S. Food and Drug Administration (FDA), and Breakthrough Therapy Designation (BTD) by China Center for Drug Evaluation (CDE), NMPA.
Vision And Mission

Our Vision
To become a leader in the field of gene therapy in China, providing innovative treatments for patients in the world.

Our Mission
To bring cutting-edge gene therapies to patients that are accessible and affordable.
Key Milestones
Management Team

Xiao Xiao
Co-Founder, Chairman and CSO, Ph.D.
Ph.D. in Molecular Biology, University of Pittsburgh
Co-founder of Bamboo / Askbio

Jane Zheng
Co-founder and CEO, Ph.D.
PhD from Institute of Neurology, Chinese Academy of Sciences
Co-founder of Genechem / Neuron Biotech

Hao Zheng
Operations, SVP
Tianjin university Pharmaceutical engineering, Bachelor

Wei Jiang
Analytical Development, Senior Director
Shanghai Institute of Biochemistry and Cell Biology, CAS, Ph.D.

Zengmin Du
Process R&D, Senior Director
East China University of Science and Technology, Ph.D.

Yue Dun
Clinical, VP
Peking University, Master